SLNSW-Olaparib in patients with metastatic castration-r...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

Full title: Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

Author/creator: Mateo, Joaquin, Porta, Nuria, Bianchini, Diletta, McGovern, Ursula, Elliott, Tony, Jones, Robert, Syndikus, Isabel, Ralph, Christy, Jain, Suneil, Varughese, Mohini, Parikh, Omi, Crabb, Simon, Robinson, Angus, McLaren, Duncan, Birtle, Alison, Tanguay, Jacob, Miranda, Susana, Figueiredo, Ines, Seed, George, Bertan, Claudia, Flohr, Penny, Ebbs, Berni, Rescigno, Pasquale, Fowler, Gemma, Ferreira, Ana, Riisnaes, Ruth, Pereira, Rita, Curcean, Andra, Chandler, Robert, Clarke, Matthew, Gurel, Bora, Crespo, Mateus, Nava Rodrigues, Daniel, Sandhu, Shahneen, Espinasse, Aude, Chatfield, Peter, Tunariu, Nina, Yuan, Wei, Hall, Emma, Carreira, Suzanne, de Bono, Johann S.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

Language: English

Formats: Articles

Publishers: England: Elsevier Ltd

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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    Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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    Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

    Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

    Full title

    Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

    Author / Creator

    Mateo, Joaquin ; Porta, Nuria ; Bianchini, Diletta ; McGovern, Ursula ; Elliott, Tony ; Jones, Robert ; Syndikus, Isabel ; Ralph, Christy ; Jain, Suneil ; Varughese, Mohini ; Parikh, Omi ; Crabb, Simon ; Robinson, Angus ; McLaren, Duncan ; Birtle, Alison ; Tanguay, Jacob ; Miranda, Susana ; Figueiredo, Ines ; Seed, George ; Bertan, Claudia ; Flohr, Penny ; Ebbs, Berni ; Rescigno, Pasquale ; Fowler, Gemma ; Ferreira, Ana ; Riisnaes, Ruth ; Pereira, Rita ; Curcean, Andra ; Chandler, Robert ; Clarke, Matthew ; Gurel, Bora ; Crespo, Mateus ; Nava Rodrigues, Daniel ; Sandhu, Shahneen ; Espinasse, Aude ; Chatfield, Peter ; Tunariu, Nina ; Yuan, Wei ; Hall, Emma ; Carreira, Suzanne ; de Bono, Johann S

    Publisher

    England: Elsevier Ltd

    Journal title

    The lancet oncology, 2020, Vol.21 (1), p.162-174

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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    English

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    Aged Analysis Biomarkers Biomarkers, Tumor - genetics Cancer Cancer therapies Care and treatment Castration Chemotherapy Clinical medicine Clinical trials Cohort Studies Deoxyribonucleic acid DNA DNA damage DNA repair DNA Repair Enzymes - genetics Drug dosages Follow-Up Studies Genes Genetic aspects Genetic research Genomics Humans Male Medical research Metastases Metastasis Middle Aged Mutation Myocardial infarction Oncology Ovarian cancer Patients Phthalazines - therapeutic use Piperazines - therapeutic use Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use Prognosis Prostate cancer Prostate-specific antigen Prostatic Neoplasms, Castration-Resistant - drug therapy Prostatic Neoplasms, Castration-Resistant - genetics Prostatic Neoplasms, Castration-Resistant - pathology Quality control Solid tumors Studies Survival Rate Toxicity Tumors

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6941219

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