SLNSW-Interplay of somatic alterations and immune infil...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

Full title: Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

Author/creator: Braun, David A, Hou, Yue, Bakouny, Ziad, Ficial, Miriam, Sant' Angelo, Miriam, Forman, Juliet, Ross-Macdonald, Petra, Berger, Ashton C, Jegede, Opeyemi A, Elagina, Liudmilla, Steinharter, John, Sun, Maxine, Wind-Rotolo, Megan, Pignon, Jean-Christophe, Cherniack, Andrew D, Lichtenstein, Lee, Neuberg, Donna, Catalano, Paul, Freeman, Gordon J, Sharpe, Arlene H, McDermott, David F, Van Allen, Eliezer M, Signoretti, Sabina, Wu, Catherine J, Shukla, Sachet A, Choueiri, Toni K.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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    Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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    Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

    Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

    Full title

    Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

    Author / Creator

    Braun, David A ; Hou, Yue ; Bakouny, Ziad ; Ficial, Miriam ; Sant' Angelo, Miriam ; Forman, Juliet ; Ross-Macdonald, Petra ; Berger, Ashton C ; Jegede, Opeyemi A ; Elagina, Liudmilla ; Steinharter, John ; Sun, Maxine ; Wind-Rotolo, Megan ; Pignon, Jean-Christophe ; Cherniack, Andrew D ; Lichtenstein, Lee ; Neuberg, Donna ; Catalano, Paul ; Freeman, Gordon J ; Sharpe, Arlene H ; McDermott, David F ; Van Allen, Eliezer M ; Signoretti, Sabina ; Wu, Catherine J ; Shukla, Sachet A ; Choueiri, Toni K

    Publisher

    United States: Nature Publishing Group

    Journal title

    Nature medicine, 2020, Vol.26 (6), p.909-918

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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    English

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    Articles

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    Adult Aged Aged, 80 and over antagonists and Inhibitors Antigen Presentation - genetics Antineoplastic Agents, Immunological - therapeutic use Cancer Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - pathology CD8 antigen CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - pathology Chromosome Deletion Chromosomes, Human, Pair 6 Chromosomes, Human, Pair 9 - genetics Class I Phosphatidylinositol 3-Kinases - genetics Clear cell-type renal cell carcinoma Clinical trials DNA-Binding Proteins - genetics Female Fluorescent Antibody Technique Gene Deletion Gene Expression Profiling Gene sequencing Genetic analysis Genomics Histocompatibility Antigens Class II - genetics Histone Demethylases - genetics Histone-Lysine N-Methyltransferase - genetics Humans Immune system Immunofluorescence Immunotherapy Infiltration Kidney cancer Kidney Neoplasms - drug therapy Kidney Neoplasms - genetics Kidney Neoplasms - immunology Kidney Neoplasms - pathology Lymphocytes Lymphocytes T Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - pathology Male Metastases Middle Aged Mutation Neoantigens Nivolumab - therapeutic use Patients PD-1 protein Phenotypes Prognosis Programmed Cell Death 1 Receptor Proteasome Endopeptidase Complex - genetics PTEN Phosphohydrolase - genetics Renal cell carcinoma Resistors Ribonucleic acid RNA Sequence Analysis, RNA TOR Serine-Threonine Kinases - genetics Transcription Factors - genetics Transcriptomics Tuberous Sclerosis Complex 1 Protein - genetics Tumor Suppressor Proteins - genetics Tumors Ubiquitin Thiolesterase - genetics Von Hippel-Lindau Tumor Suppressor Protein - genetics Whole Exome Sequencing

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7499153

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