SLNSW-Loss of function of the mitochondrial peptidase P...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Full title: Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Author/creator: Pérez, María José, Ivanyuk, Dina, Panagiotakopoulou, Vasiliki, Di Napoli, Gabriele, Kalb, Stefanie, Brunetti, Dario, Al-Shaana, Rawaa, Kaeser, Stephan A, Fraschka, Sabine Anne-Kristin, Jucker, Mathias, Zeviani, Massimo, Viscomi, Carlo, Deleidi, Michela.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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    Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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    Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

    Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

    Full title

    Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

    Author / Creator

    Pérez, María José ; Ivanyuk, Dina ; Panagiotakopoulou, Vasiliki ; Di Napoli, Gabriele ; Kalb, Stefanie ; Brunetti, Dario ; Al-Shaana, Rawaa ; Kaeser, Stephan A ; Fraschka, Sabine Anne-Kristin ; Jucker, Mathias ; Zeviani, Massimo ; Viscomi, Carlo ; Deleidi, Michela

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    England: Nature Publishing Group

    Journal title

    Molecular psychiatry, 2021, Vol.26 (10), p.5733-5750

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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    English

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    Alzheimer Disease - genetics Alzheimer's disease Alzheimers disease Amyloid beta-Peptides Amyloid precursor protein Apoptosis Astrocytes Cell biology Cell death Cerebellar ataxia Cerebellum Cerebral cortex Cognitive ability Development and progression Diseases Genetic aspects Health aspects Humans Immune clearance Induced Pluripotent Stem Cells Inhibitory postsynaptic potentials Metalloendopeptidases Metalloproteinase Mitochondria Neurodegenerative diseases Neurogenesis Neuroscience Organoids Pathology Peptidase Physiological aspects Pitrilysin Pluripotency Proteases Protein folding Proteins Quality control Stem cells Tau protein Transcription

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758476

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